Biochemical Test of Vibrio cholerae


Vibrio cholerae is a Gram-negative, comma-shaped bacterium that causes cholera, a severe diarrheal disease that can be fatal if left untreated. Cholera is transmitted through contaminated water or food, and affects millions of people worldwide every year. The World Health Organization estimates that there were 1.3 million cases and 21,000 deaths due to cholera in 2019.

Vibrio cholerae belongs to the family Vibrionaceae, which includes other pathogenic species such as Vibrio parahaemolyticus and Vibrio vulnificus. Vibrio cholerae has two biotypes: classical and El Tor. Each biotype has several serogroups, which are distinguished by their O antigens on the cell surface. The most common serogroups that cause cholera are O1 and O139.