Heat coagulation test of proteins


Heat coagulation test of proteins is a biochemical test that detects the presence of proteins that can form an insoluble mass when heated at their isoelectric pH. The test is based on the principle that some proteins, such as albumin and globulin, undergo structural changes when exposed to heat and acid, resulting in the aggregation of their polypeptide chains. The test is simple, quick and inexpensive, and can be used to qualitatively or quantitatively measure the amount of coagulable proteins in a sample. The test is commonly used to diagnose proteinuria, a condition where excess proteins are excreted in the urine due to kidney damage or other diseases.