Biochemical Test of Fusobacterium necrophorum


Fusobacterium necrophorum is a species of bacteria that belongs to the Fusobacteriaceae family. It is a rod-shaped, Gram-negative, obligate anaerobe that can cause various infections in humans and animals.

F. necrophorum is commonly found in the oral cavity, gastrointestinal tract, and female genital tract of healthy individuals. However, under certain conditions, it can invade the mucosal barriers and enter the bloodstream, leading to serious complications such as Lemierre`s syndrome, meningitis, thrombosis, and abscesses.

Lemierre`s syndrome is a rare but potentially fatal condition that occurs when F. necrophorum infects the throat and spreads to the internal jugular vein, causing inflammation and blood clots. The clots can then travel to other organs such as the lungs, brain, liver, or joints, resulting in septic emboli and multi-organ failure.

F. necrophorum is also a cause of animal diseases such as thrush in horses and scald in sheep. Thrush is an infection of the hoof that causes foul-smelling discharge and lameness. Scald is an infection of the skin between the hooves that causes pain and inflammation. Both conditions are associated with poor hygiene and environmental factors.

F. necrophorum is a challenging pathogen to diagnose and treat because of its anaerobic nature, its similarity to other bacteria, and its resistance to some antibiotics. Therefore, it is important to understand its biochemical characteristics and mechanisms of pathogenicity. In this article, we will discuss the fermentation and enzymatic reactions of F. necrophorum and how they contribute to its virulence and survival.