Non-Specific Immune Response


The human body is constantly exposed to various microorganisms that can cause infections and diseases. However, not all of these microorganisms are able to enter the body and cause harm. This is because the body has a series of defense mechanisms that prevent or limit the invasion of pathogens. These defense mechanisms are called non-specific or innate immune response, as they do not require prior exposure or recognition of specific antigens. They are present from birth and act as the first line of defense against infection.

The non-specific immune response can be divided into two categories: defense mechanisms that precede infection and defense mechanisms that are evoked by infection. The former are the ones that prevent or reduce the entry of pathogens into the body, while the latter are the ones that eliminate or contain the pathogens that have already entered the body. In this article, we will focus on the defense mechanisms that precede infection and how they protect the body from various types of pathogens. These defense mechanisms include anatomical barriers, physiological barriers, cellular barriers and complements. We will discuss each of these in detail in the following sections.