Mass Spectrometry (MS)- Principle, Working, Parts, Steps, Uses


Mass spectrometry (MS) is a powerful and versatile technique that can be used to identify and quantify the chemical composition of matter. It can analyze samples ranging from atoms and molecules to complex mixtures and biological macromolecules. Mass spectrometry works by converting the sample into charged particles, called ions, and separating them based on their mass-to-charge ratio (m/z) . The resulting mass spectrum shows the relative abundance of each ion as a function of its m/z value. By comparing the mass spectrum with known reference data, the identity and structure of the sample can be determined. Mass spectrometry has many applications in various fields, such as environmental monitoring, geochemistry, chemical and petrochemical industry, biotechnology, medicine, and forensic science . In this article, we will explain the principle, working, parts, steps, and uses of mass spectrometry in more detail.